Abingworth
Abingworth is a transatlantic life-sciences investment firm founded in 1973 and one of the longest-established dedicated biotechnology and medical-technology investors in Europe. Headquartered in London with offices in New York and San Francisco, it backs seed- to development-stage biopharmaceutical, biotechnology and medical-technology companies across the United States, Europe and Asia. Over its history the firm has invested in more than 185 life-science companies, generating over 75 public listings and more than 50 trade-sale exits. Abingworth invests through early- and late-stage venture capital, venture investments in public equities, and a Clinical Co-Development strategy that funds late-stage drug trials in exchange for milestone-based returns. The Carlyle Group agreed to acquire Abingworth in April 2022 and completed the transaction in August 2022 for approximately USD 190 million; Abingworth continues to operate under its own brand, investment team and named funds as Carlyle's life-sciences venture platform and manages approximately USD 2 billion. It is regulated by the UK Financial Conduct Authority under firm reference number 453934.
Key facts
Recent exits
Coverage notes
6 funds tracked, 39 portfolio companies (32 active · 7 realized). Verified weekly from public filings and deal announcements.
Funds & portfolio
Every fund Abingworth has raised, with its portfolio companies. Hand-checked from public filings.
Abingworth Bioventures IXVC2023 · 3yr3 active
Unrealized
3 held| Company | Sector | Geo | Entry |
|---|---|---|---|
| Addition Therapeutics | Biotech | US | 2025 |
| cAMPfield | Biotech | US | 2026 |
| R1 Therapeutics | Biotech | US | 2026 |
Abingworth Clinical Co-Development Co-Investment FundLife Sciences VC2023 · 3yr€327M0 active
No portfolio companies tracked yet.
Abingworth Bioventures 8Life Sciences VC2021 · 5yr€428M14 active · 2 realized
Unrealized
14 held| Company | Sector | Geo | Entry |
|---|---|---|---|
| AdvanCell | Biotech | Australia | 2025 |
| Antares Therapeutics | Biotech | US | 2025 |
| Ascend Gene & Cell Therapies | Biotech | UK | 2023 |
| Cytospire Therapeutics | Biotech | UK | 2026 |
| Entact Bio | Biotech | US | 2022 |
| Glycomine | Biotech | US | 2021 |
| HilleVax | Healthcare | US | 2021 |
| Iambic Therapeutics | AI/ML | US | 2023 |
| Nido Biosciences | Biotech | US | 2023 |
| Pathalys Pharma | Biotech | US | 2023 |
| Solve Therapeutics | Biotech | US | 2025 |
| Timberlyne Therapeutics | Healthcare | US | 2025 |
| Vera Therapeutics | Biotech | US | 2021 |
| Wugen | Biotech | US | 2021 |
Realized
2 exits| Company | Sector | Geo | Entry | Exit | Type | Buyer | MOIC |
|---|---|---|---|---|---|---|---|
| Myricx Bio | Biotech | UK | 2024 | 2026 | Trade Sale | – | |
| OnKure Therapeutics | Healthcare | US | 2023 | 2024 | IPO | – | – |
Abingworth Clinical Co-Development Fund 2Life Sciences VC2021 · 5yr€535M2 active
Unrealized
2 held| Company | Sector | Geo | Entry |
|---|---|---|---|
| Launch Therapeutics | Biotech | US | 2022 |
| Opthea | Biotech | Australia | 2022 |
Abingworth Bioventures VIILife Sciences VC2018 · 8yr€290M9 active · 1 realized
Unrealized
9 held| Company | Sector | Geo | Entry |
|---|---|---|---|
| Adicet Bio | Biotech | US | 2021 |
| Atsena Therapeutics | Biotech | US | 2020 |
| Jasper Therapeutics | Healthcare | US | 2019 |
| Orbus Therapeutics | Healthcare | US | 2020 |
| Phathom Pharmaceuticals | Healthcare | US | 2019 |
| Scorpion Therapeutics | Biotech | US | 2020 |
| Soteria Biotherapeutics | Healthcare | US | 2021 |
| Spruce Biosciences | Biotech | US | 2020 |
| Trishula Therapeutics | Biotech | US | 2020 |
Abingworth Bioventures VILife Sciences VC2014 · 12yr€345M4 active · 4 realized
Unrealized
4 held| Company | Sector | Geo | Entry |
|---|---|---|---|
| Exicure | Biotech | US | 2019 |
| Median Technologies | Healthcare | France | 2015 |
| Tizona Therapeutics | Biotech | US | 2016 |
| Venatorx Pharmaceuticals | Healthcare | US | 2022 |
Realized
4 exits| Company | Sector | Geo | Entry | Exit | Type | Buyer | MOIC |
|---|---|---|---|---|---|---|---|
| Avedro | MedTech | US | 2014 | 2019 | Trade Sale | – | |
| eFFECTOR Therapeutics | Biotech | US | 2013 | 2021 | IPO | – | |
| GenSight Biologics | Biotech | France | 2014 | 2016 | IPO | – | – |
| Soleno Therapeutics | Biotech | US | 2018 | 2026 | Trade Sale | – |
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About Abingworth
Abingworth is a transatlantic life sciences venture capital specialist with more than $2 billion of assets under management as of December 2024 (raised nearly $1 billion across 2021-2024 for life sciences plus a separately advised $1.5 billion Carlyle-backed clinical trials fund), headquartered in London with offices in New York and San Francisco. The firm was founded in 1973 with a 50 plus year life sciences specialist track record covering 185 plus companies, 50 plus M&A transactions and 75 plus IPOs. Abingworth was acquired by The Carlyle Group in August 2022 and operates as an independent unit and LLP affiliate.
Investment thesis
Abingworth deploys capital through 12 plus Abingworth Bioventures funds (ABV VII, ABV 8, plus the Carlyle-Abingworth clinical trials vehicle), targeting transatlantic life sciences venture capital from seed to development stages. The platform combines traditional VC investing with innovative structures including Venture Investments in Public Equities (VIPEs), Clinical Co-Development and royalty-based late-stage clinical trial financing. Sector focus spans biopharma, biotech therapeutics and gene and cell therapy, with geographic deployment across US and UK core plus broader European and Asia-Pacific coverage. The Carlyle balance sheet integration enables clinical co-development and royalty financing structures unavailable to traditional VC platforms.
Recent activity
Recent realised exits include biopharma and respiratory therapeutics (Verona Pharma, 2025) and biotech immunology (Escient Pharmaceuticals, 2024). Recent investments include Solve Therapeutics Series C (November 2025), Addition Therapeutics (gene and cell therapy, 2025) and Iambic Therapeutics follow-on (2025), with 9 investments completed in 2025. The platform continues active deployment across the transatlantic life sciences franchise. Detailed buyer names and multiple data available on Pro at €29/month.
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